Mental health
Spravato® treatment in Eugene
In-clinic Spravato (esketamine) nasal spray treatment for adults with treatment-resistant depression, with a prescriber on site and monitoring after every dose.
What Spravato is
Spravato® (esketamine) is a prescription nasal spray for adults with treatment-resistant depression. It can be used on its own or together with an oral antidepressant.
It is offered at our Eugene clinic when clinically appropriate. It is not right for everyone. Your provider will talk with you about whether it may be a fit, along with its benefits and risks. Individual results vary.
Who it may help
- Adults with depression that has not improved enough with other treatments
- People who want to learn whether Spravato is a safe choice for them
- People who want their depression care connected to the rest of their health care
Eligibility depends on your history, other treatments you've tried and your insurance.
What a treatment day looks like
In the clinic
- We check your blood pressure before your dose
- You use the nasal spray yourself, with our team right there
- Our team monitors you for at least 2 hours, including your blood pressure and breathing
- You leave once your provider says you are ready to go
Before you come
- Skip food for 2 hours before your treatment
- Skip drinks for 30 minutes before
- Plan a ride home. You can't drive until the next day, after a restful sleep
How often
Treatment usually starts twice a week for the first 4 weeks, then weekly, then weekly or every 2 weeks. After 4 weeks, your provider checks with you how it is working and whether to continue.
Safety comes first
Spravato is only available through a restricted safety program called the Spravato REMS, and every dose is given in a certified clinic. That is why you stay with us after each treatment.
Common side effects include feeling disconnected or dissociated, dizziness, nausea, sleepiness and a rise in blood pressure. Your provider will review your health history and medications before you start.
Who provides this care
Rachel Leonhardy, APRN, FNP-C is the on-site prescriber for Spravato at our Eugene clinic.
If you already work with one of our psychiatric nurse practitioners, your mental health medication management provider can talk with you about a Spravato evaluation.
Insurance and cost
Spravato is billed to insurance only, and your cost depends on your plan. Many plans, including OHP, need prior authorization before treatment starts.
Insurance participation varies by provider, service, location and plan. Please call or text (541) 214-2786 so we can confirm your specific plan and benefits.
Good to know
Getting home after treatment
You need someone to drive you home. Don't drive or use machinery until the next day, after a restful sleep.
Your other medicines
Bring a full list of your medicines to your evaluation. Some medicines can raise your blood pressure or make you sleepier with Spravato, so your provider will review them with you.
Where treatment happens
Every Spravato dose is given in person at our Eugene clinic, 71 Centennial Loop Ste A. It is not taken at home.
Crisis help
Spravato is not an emergency service. If you or someone you know is in a mental-health crisis, call or text 988. For a medical emergency, call 911.
Related services
Mental Health Medication Management
Psychiatric evaluation and medication management with psychiatric nurse practitioners.
Learn more →Primary Care
Checkups, ongoing conditions, prescriptions and preventive care for adults.
Learn more →Eugene Clinic
Address, hours and what we offer in Eugene.
Learn more →Clinical content reviewed by Revitalized Wellness clinical leadership · Updated November 2026. Source: Spravato prescribing information.